Light Therapy for Wound Care

georgeu

6 Posts
 
Posted - 02/08/2006 :  12:46:17  Show Profile  Reply with Quote
Is there anyone out there utilizing Anodyne's Infared Therapy? We had an Anodyne rep come to our clinic and present it to us. We are wondering about its effectiveness and the issues with getting reimbursed. Any info would be deeply appreciated.
Thanks
George

anodyne

1 Posts
 
Posted - 09/14/2006 :  14:16:00  Show Profile  Visit anodyne's Homepage  Reply with Quote
When Medicare carriers/intermediaries and private insurers cover Anodyne
Therapy, it is covered under infrared, one or more areas (CPT 97026). Some
Medicare carriers cover Anodyne Therapy, some do not. This will vary by
region or state, and/or which Medicare intermediary the facility submits
bills to. Anodyne Therapy is an infrared therapy. Infrared is only
considered a skilled therapy under most Medicare LCD's if the patient is at
higher risk of a burn--i.e. insensate areas (i.e. neuropathy), poor
circulation or an open wound. Always document functional complication ICD-9
codes appropriate for infrared if they are present (i.e. pain in limb --
729.5, range of motion/contracture -- 718.4 - 718.49, swelling in limb --
729.81, muscle spasm -- 728.85), not the underlying diagnosis.

Additional "Reimbursement Information" can be found on the Anodyne Therapy
website:
www.anodynetherapy.com Click on the area "HealthCare Professionals", then
scroll down and Click under "more information on Reimbursement", Scroll down
to "Reimbursement Information".

Sincerly,
Marianne Young--Anodyne Clinical Consultant
800-521-6664 ex. 334
fax: 262-245-5056
marianneyoung@anodynetherapy.com
www.anodynetherapy.com

SCPT

USA
10 Posts
 
Posted - 11/06/2006 :  15:58:47  Show Profile  Reply with Quote
FYI- Great links to articles for wound care and utilizing lasers

Wound healing of animal and human body sport and traffic accident injuries using low-level laser therapy treatment: a randomized clinical study of seventy-four patients with control group.
CONCLUSION: In addition to accelerated wound healing, the main advantages of LLLT for postoperative sport- and traffic-related injuries include prevention of side effects of drugs, significantly accelerated functional recovery, earlier return to work, training and sport competition compared to the control group of patients, and cost benefit.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11800105&query_hl=10&itool=pubmed_DocSum

A randomized, placebo controlled trial of low level laser therapy for activated Achilles tendonitis with microdialysis measurement of peritendinous prostaglandin E2 concentrations.
CONCLUSION: LLLT at a dose of 5.4 J per point can reduce inflammation and pain in activated Achilles tendonitis. LLLT may therefore have potential in the management of diseases with an inflammatory component.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16371497&query_hl=29&itool=pubmed_docsum

Low-Level Laser Therapy Facilitates Superficial Wound Healing in Humans: A Triple-Blind, Sham-Controlled Study.
CONCLUSIONS: The LLLT resulted in enhanced healing as measured by wound contraction. The untreated wounds in subjects treated with LLLT contracted more than the wounds in the sham group, so LLLT may produce an indirect healing effect on surrounding tissues. These data indicate that LLLT is an effective modality to facilitate wound contraction of partial-thickness wounds.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15496990&query_hl=39&itool=pubmed_docsum

Efficacy of 904 nm gallium arsenide low-level laser therapy in the management of chronic myofascial pain in the neck: a double-blind and randomize-controlled trial.
CONCLUSION: This study revealed that short-period application of LLLT is effective in pain relief and in the improvement of functional ability and QoL in patients with MPS. Copyright 2004 Wiley-Liss, Inc.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15389743&query_hl=18&itool=pubmed_DocSum

Effect of NASA light-emitting diode irradiation on wound healing.
CONCLUSION: We believe that the use of NASA LED for light therapy alone, and in conjunction with hyperbaric oxygen, will greatly enhance the natural wound healing process, and more quickly return the patient to a preinjury/illness level of activity. This work is supported and managed through the NASA Marshall Space Flight Center-SBIR Program.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11776448&query_hl=7&itool=pubmed_docsum

Carpal tunnel syndrome pain treated with low-level laser and microamperes transcutaneous electric nerve stimulation: A controlled study.
CONCLUSIONS: This new, conservative treatment was effective in treating CTS pain; larger studies are recommended. Copyright 2002 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12098159&query_hl=29&itool=pubmed_docsum

Efficacy of low power laser therapy and exercise on pain and functions in chronic low back pain.
CONCLUSIONS: Low power laser therapy seemed to be an effective method in reducing pain and functional disability in the therapy of chronic LBP. Copyright 2003 Wiley-Liss, Inc.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12605431&query_hl=18&itool=pubmed_DocSum

Efficacy of different therapy regimes of low-power laser in painful osteoarthritis of the knee: a double-blind and randomized-controlled trial.
CONCLUSIONS: Our study demonstrated that applications of LPLT in different dose and duration have not affected results and both therapy regimes were a safe and effective method in treatment of knee OA. Copyright 2003 Wiley-Liss, Inc.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14677160&query_hl=18&itool=pubmed_DocSum

The efficacy of laser therapy in wound repair: a meta-analysis of the literature.
CONCLUSION: We conclude that laser therapy is an effective tool for promoting wound repair.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15315732&query_hl=10&itool=pubmed_DocSum

Arthralgia of the temporomandibular joint and low-level laser therapy.
CONCLUSION: This study showed the effectiveness of complex non-invasive treatment in patients with arthralgia of the TMJ. The analgesic and anti-inflammatory effects of LLLT were confirmed by infrared thermography.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16942435&query_hl=1&itool=pubmed_docsum

Management of mouth opening in patients with temporomandibular disorders through low-level laser therapy and transcutaneous electrical neural stimulation.
RESULTS: A significant improvement in the range of motion for both therapies was observed immediately after treatment. Comparing the two methods, the values obtained after LLLT were significantly higher than those obtained after TENS (p < 0.01). CONCLUSIONS: Both methods are effective to improve mouth opening. Comparing the two methods, LLLT was more effective than TENS applications.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=16503788&query_hl=1&itool=pubmed_docsum

Effectiveness of low-level laser therapy in temporomandibular disorder.
CONCLUSION: Low-level laser therapy can be considered as an alternative physical modality in the management of temporomandibular disorder.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=12737331&query_hl=1&itool=pubmed_docsum

Laser technology in orthopedics: preliminary study on low power laser therapy to improve the bone-biomaterial interface.
CONCLUSION: These preliminary positive results seem to support the hypothesis that LPL treatment can be considered a good tool to enhance the bone-implant interface in orthopedic surgery
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11831596&query_hl=10&itool=pubmed_DocSum

Effect of laser therapy on attachment, proliferation and differentiation of human osteoblast-like cells cultured on titanium implant material.
CONCLUSION: These results showed that in response to LLLT, HOB cultured on titanium implant material had a tendency towards increased cellular attachment, proliferation, differentiation and production of TGF-beta(1), indicating that in vitro LLLT can modulate the activity of cells and tissues surrounding implant material.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15621240&query_hl=18&itool=pubmed_DocSum

Efficacy of low power laser therapy in fibromyalgia: a single-blind, placebo-controlled trial.
CONCLUSION: Our study suggests that laser therapy is effective on pain, muscle spasm, morning stiffness, and total tender point number in fibromyalgia and suggests that this therapy method is a safe and effective way of treatment in the cases with fibromyalgia.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11845369&query_hl=18&itool=pubmed_DocSum

Carpal tunnel syndrome pain treated with low-level laser and microamperes transcutaneous electric nerve stimulation: A controlled study.
CONCLUSIONS: This new, conservative treatment was effective in treating CTS pain; larger studies are recommended. Copyright 2002 by the American Congress of Rehabilitation Medicine and the American Academy of Physical Medicine and Rehabilitation
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12098159&query_hl=18&itool=pubmed_DocSum

The effect of laser irradiation for nucleus pulposus: an experimental study.
CONCLUSIONS: One of the mechanisms thought to be responsible for PLDD's effectiveness is a decrease in the chemical factors through protein alteration in the intervertebral disc by laser irradiation.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15845216&query_hl=18&itool=pubmed_DocSum

Low level laser therapy in primary Raynaud's phenomenon--results of a placebo controlled, double blind intervention study.
CONCLUSION: Low level laser therapy reduces frequency and severity of Raynaud attacks. The effect is most pronounced in patients with signs of decreased threshold for vasospasm and less effective in patients with delayed hyperemia.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15570642&query_hl=18&itool=pubmed_DocSum

The efficacy of low-power lasers in tissue repair and pain control: a meta-analysis study.
CONCLUSIONS: These findings mandate the conclusion that laser phototherapy is a highly effective therapeutic armamentarium for tissue repair and pain relief.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15345176&query_hl=10&itool=pubmed_DocSum

Treatment of medial and lateral epicondylitis--tennis and golfer's elbow--with low level laser therapy: a multicenter double blind, placebo-controlled clinical study on 324 patients.
CONCLUSIONS: This clinical study has demonstrated that the best results are obtained using combination treatment (i.e., TPs and scanner technique). Good results are obtained from adequate treatment technique correctly applied, individual energy doses, adequate medical education, clinical experience, and correct approach of laser therapists. We observed that under- and overirradiation dosage can result in the absence of positive therapy effects or even opposite, negative (e.g., inhibitory) effects. The current clinical study provides further evidence of the efficacy of LLLT in the management of lateral and medial epicondylitis.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9743652&query_hl=18&itool=pubmed_DocSum

Low-level laser therapy with trigger points technique: a clinical study on 243 patients.
CONCLUSION: Results measured according to VAS/VRS/PTM: in acute pain, diminished more than 70%; in chronic pain more than 60%. Clinical effectiveness (success or failure) depends on the correctly applied energy dose--over/underdosage produces opposite, negative effects on cellular metabolism. We did not observe any negative effects on the human body and the use of analgesic drugs could be reduced or completely excluded. LLLT suggests that the laser beam can be used as monotherapy or as a supplementary treatment to other therapeutic procedures for pain treatment.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9456632&query_hl=18&itool=pubmed_DocSum

Efficacy of low level laser therapy in myofascial pain syndrome: an algometric and thermographic evaluation.
CONCLUSIONS: LLLT seemed to be beneficial for pain in MPS by using algometry and thermography.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14677161&query_hl=18&itool=pubmed_DocSum

Management of mouth opening in patients with temporomandibular disorders through low-level laser therapy and transcutaneous electrical neural stimulation.
CONCLUSIONS: Both methods are effective to improve mouth opening. Comparing the two methods, LLLT was more effective than TENS applications.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16503788&query_hl=18&itool=pubmed_docsum

Efficacy of low level laser therapy on neurosensory recovery after injury to the inferior alveolar nerve.
CONCLUSION : Low level laser therapy seemed to be conducive to the reduction of long-standing sensory nerve impairment following third molar surgery. Further studies are worthwhile regarding the clinical application of this treatment modality.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16480503&query_hl=18&itool=pubmed_docsum

The effect of low-level Nd:YAG laser energy on adult articular cartilage in vitro.
CONCLUSION: These findings indicate that exposure to low-level noncontact Nd:YAG laser energy promotes a significant stimulation of cartilage matrix synthesis. However, a single exposure may not be sufficient to promote a sustained upregulation of cartilage metabolism.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=1550649&query_hl=10&itool=pubmed_DocSum

Biostimulation of wound healing in vivo by a helium-neon laser.
CONCLUSION: Results demonstrated a considerable improvement in the tensile strength of the laser-irradiated wounds at 1 and 2 weeks. Furthermore, the total collagen content was significantly increased at 2 months when compared with control wounds. These results suggest a beneficial effect of the helium-neon laser on wound healing in vivo.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3827131&query_hl=49&itool=pubmed_DocSum

Low level laser therapy (Classes I, II and III) for treating rheumatoid arthritis.
CONCLUSIONS: LLLT could be considered for short-term treatment for relief of pain and morning stiffness for RA patients, particularly since it has few side-effects. Clinicians and researchers should consistently report the characteristics of the LLLT device and the application techniques used. New trials on LLLT should make use of standardized, validated outcomes. Despite some positive findings, this meta-analysis lacked data on how LLLT effectiveness is affected by four important factors: wavelength, treatment duration of LLLT, dosage and site of application over nerves instead of joints. There is clearly a need to investigate the effects of these factors on LLLT effectiveness for RA in randomized controlled clinical trials.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16235295&query_hl=62&itool=pubmed_docsum

Low-intensity laser therapy for painful symptoms of diabetic sensorimotor polyneuropathy: a controlled trial.
CONCLUSIONS: Although an encouraging trend was observed with LILT, the study results do not provide sufficient evidence to recommend this treatment for painful symptoms of DSP.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15047649&query_hl=62&itool=pubmed_DocSum

Influence of low level laser therapy on wound healing and its biological action upon myofibroblasts.
CONCLUSIONS: Laser therapy reduced the inflammatory reaction, induced increased collagen deposition and a greater proliferation of myofibroblasts in experimental cutaneous wounds
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12605432&query_hl=10&itool=pubmed_DocSum

Effect of NASA light-emitting diode irradiation on molecular changes for wound healing in diabetic mice.
CONCLUSION: We believe that the use of NASA light-emitting diodes (LED) for light therapy will greatly enhance the natural wound healing process, and more quickly return the patient to a preinjury/illness level of activity. This work is supported and managed through the Defense Advanced Research Projects Agency (DARPA) and NASA Marshall Space Flight Center-SBIR Program.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12737646&query_hl=50&itool=pubmed_docsum

Laser technology in orthopedics: preliminary study on low power laser therapy to improve the bone-biomaterial interface.
CONCLUSION: These preliminary positive results seem to support the hypothesis that LPL treatment can be considered a good tool to enhance the bone-implant interface in orthopedic surgery
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11831596&query_hl=18&itool=pubmed_DocSum

The influence of low-level laser therapy on biomodulation of collagen and elastic fibers.
CONCLUSION: In this study, the authors concluded that low-level laser therapy contributed to a larger expression of collagen and elastic fibers during the early phases of the wound healing process.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15107911&query_hl=10&itool=pubmed_DocSum

Effect of low-level Er:YAG laser irradiation on cultured human gingival fibroblasts.
CONCLUSIONS: Our results showed that the low-level Er:YAG laser irradiation stimulates the proliferation of cultured gingival fibroblasts. The optimal stimulative energy density was found to be 3.37 J/cm(2). This result suggests that Er:YAG laser irradiation may be of therapeutic benefit for wound healing.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15974841&query_hl=10&itool=pubmed_docsum

Therapeutic low energy laser improves the mechanical strength of repairing medial collateral ligament. (in rats)
CONCLUSIONS: A single dose of low energy laser therapy improves the UTS and stiffness of repairing MCL at 3 and 6 weeks after injury. Copyright 2002 Wiley-Liss, Inc.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12210592&query_hl=10&itool=pubmed_DocSum

The effect of low level laser irradiation on implant-tissue interaction. In vivo and in vitro studies.
CONCLUSION: LLLT can promote bone healing and bone mineralization and thus may be clinically beneficial in promoting bone formation in skeletal defects. It may be also used as additional treatment for accelerating implant healing in bone. LLLT can modulate the primary steps in cellular attachment and growth on titanium surfaces. Multiple doses of LLLT can improve LLLT efficacy, accelerate the initial attachment and alter the behavior of human gingival fibroblasts cultured on titanium surfaces.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15906852&query_hl=10&itool=pubmed_docsum

Low-level laser therapy (LLLT) efficacy in post-operative wounds.
CONCLUSION: LLLR with wavelength of 904 nm to stimulate postoperative aseptic wounds (early scar) is efficient in both cases of cutting plague.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15782037&query_hl=10&itool=pubmed_docsum

Enhancement of bone formation in rat calvarial bone defects using low-level laser therapy.
CONCLUSION: LLLT may enhance bone formation in rat calvarial bone defects.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15184850&query_hl=10&itool=pubmed_DocSum

Low-level laser irradiation promotes proliferation and differentiation of human osteoblasts in vitro.
CONCLUSION: We conclude that LLLT promotes proliferation and maturation of human osteoblasts in vitro. These results may have clinical implications.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15910179&query_hl=18&itool=pubmed_DocSum

Low-level laser therapy accelerates collateral circulation and enhances microcirculation.
CONCLUSIONS: The results indicated that LLLT accelerated collateral circulation and enhanced microcirculation and seemed to be unique in the normalization of the functional features of the injured area, which could lead to occlusion of the regional blood vessels.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15954817&query_hl=18&itool=pubmed_DocSum

Low Level Laser Therapy (LLLT) as an Effective Therapeutic Modality for Delayed Wound Healing.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16387711&query_hl=18&itool=pubmed_DocSum

Laser application effects on the bite strength of the masseter muscle, as an orofacial pain treatment.
CONCLUSIONS: These results suggest that low-level laser application is an effective tool for the treatment of patients with orofacial pain.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16144479&query_hl=18&itool=pubmed_DocSum

Effect of 830-nm laser light on the repair of bone defects grafted with inorganic bovine bone and decalcified cortical osseous membrane.
CONCLUSION: It is concluded that LLLT had a positive effect on the repair of bone defect submitted the implantation of graft.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14709224&query_hl=10&itool=pubmed_DocSum

Evaluation of low level laser therapy on primary healing of experimentally induced full thickness teat wounds in dairy cattle.
CONCLUSION: The LLLT affects various aspects of the healing process, including minimizing inflammation, formation of edema, improvement of skin regeneration and enhancement of collagen synthesis. CLINICAL RELEVANCE: The LLLT could accelerate healing of sutured wounds of the teat in dairy cattle.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=9068161&query_hl=10&itool=pubmed_DocSum

Low level laser therapy (Classes I, II and III) for treating osteoarthritis.
CONCLUSIONS: For OA, the results are conflicting in different studies and may depend on the method of application and other features of the LLLT application. Clinicians and researchers should consistently report the characteristics of the LLLT device and the application techniques used. New trials on LLLT should make use of standardized, validated outcomes. Despite some positive findings, this meta-analysis lacked data on how LLLT effectiveness is affected by four important factors: wavelength, treatment duration of LLLT, dosage and site of application over nerves instead of joints. There is clearly a need to investigate the effects of these factors on LLLT effectiveness for OA in randomized controlled clinical trials.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15266461&query_hl=62&itool=pubmed_DocSum

Effect of laser irradiation of diode laser on healing of surgical wounds in rats
CONCLUSION: the healing of stimulated wounds was accelerated in comparison with controls. The histological evaluation showed earlier regress of inflammatory phase, faster finishing of reepithelization and acceleration in maturation phase. Presented experimental study completes the previous study and achieves the positive effect of biostimulation on all phases of skin wound healing in vivo.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16218351&query_hl=10&itool=pubmed_docsum

Does the use of low-level laser influence wound healing in chronic venous leg ulcers?
CONCLUSION: These study results suggest that low-level laser does not stimulate wound healing in venous leg ulcers. Further controlled studies are needed to clarify the efficacy of low-level laser treatment as a wound-healing stimulant.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16178295&query_hl=10&itool=pubmed_docsum

Effect of low-level laser therapy on Candida albicans growth in patients with denture stomatitis.
CONCLUSION: LLLT is effective in the treatment of denture stomatitis. http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15954824&query_hl=18&itool=pubmed_DocSum

Laser stimulation on bone defect healing: an in vitro study.
CONCLUSION: These in vitro results suggest that Ga-Al-As LPL treatment may play a positive role in bone defect healing.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12181636&query_hl=10&itool=pubmed_DocSum

Effects of 630-, 660-, 810-, and 905-nm laser irradiation delivering radiant exposure of 1-50 J/cm2 on three species of bacteria in vitro.
CONCLUSION: LILT applied to wounds, delivering commonly used wavelengths and radiant exposures in the range of 1-20 J/cm(2), could produce changes in bacterial growth of considerable importance for wound healing. A wavelength of 630 nm appeared to be most commonly associated with bacterial inhibition. The findings of this study might be useful as a basis for selecting LILT for infected wounds.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12513919&query_hl=10&itool=pubmed_DocSum

Contribution of phototherapy to the treatment of episiotomies.
CONCLUSION: The work demonstrated high healing effects with minimum secondary complications in the treatment of episiotomies using a therapeutic laser at an energy density of 2 J/cm(2). The application of polarized light at an energy density of 5 J/cm(2) also exerted favorable therapeutic effects.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12614558&query_hl=67&itool=pubmed_docsum

Low-level laser irradiation promotes proliferation and differentiation of human osteoblasts in vitro.
CONCLUSION: We conclude that LLLT promotes proliferation and maturation of human osteoblasts in vitro. These results may have clinical implications.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15910179&query_hl=18&itool=pubmed_DocSum

Evidence of changes in sural nerve conduction mediated by LED (light emitting diode) irradiation.
CONCLUSION: LED irradiation, applied to intact skin at the described irradiation parameters, produces an immediate and localized effect upon conduction characteristics in underlying nerves. Therefore, the outcome of this in vivo experiment yields a potential explanation for pain relief induced by LED.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15895289&query_hl=18&itool=pubmed_DocSum

Low-level laser for prevention and therapy of oral mucositis induced by chemotherapy or radiotherapy.
CONCLUSION: low-level laser therapy may be useful in decreasing the severity of chemotherapy-associated or radiotherapy-associated mucositis is substantial
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15818167&query_hl=18&itool=pubmed_DocSum

Use of laser for rectal lesions in poor-risk patients.
CONCLUSIONS: Outpatient laser therapy is safe, repeatable, and effective in the local control of rectal lesions.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15619488&query_hl=18&itool=pubmed_DocSum

Low-level laser irradiation stimulates mitochondrial membrane potential and disperses subnuclear promyelocytic leukemia protein.
CONCLUSIONS: These changes reflect a biostimulative boost that causes a shift of the cell from a quiescent to an activated stage in the cell cycle heralding proliferation and suppression of inflammation. Further characterization of MMP kinetics may provide a quantitative basis for assessment of the effect of LLLI in the clinical setting.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15611960&query_hl=18&itool=pubmed_DocSum

Low-level laser treatment can reduce edema in second-degree ankle sprains.
CONCLUSIONS: LLLT combined with RICE can reduce edema in second-degree ankle sprains.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15165387&query_hl=18&itool=pubmed_DocSum

Laser biostimulation in the treatment of pleurisy
CONCLUSION: 1. Patients with pleurisy undergoing laser stimulation presented with faster resorption of effusion and remission of the subjective symptoms, as well as significant decrease of biochemical acute inflammation parameters in the peripheral blood and therefore with faster recovery. 2. In patients with pleurisy laser treatment increases regenerative mechanisms of the pleural surface, thus decreasing the quantity of formed adhesions and resulting in better mobility of the diaphragm.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15080043&query_hl=18&itool=pubmed_DocSum

Efficacy of low level laser therapy in reducing postoperative pain after endodontic surgery-- a randomized double blind clinical study.
CONCLUSION: Low level laser therapy can be beneficial for the reduction of postoperative pain.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14758818&query_hl=18&itool=pubmed_DocSum

Increased fibroblast proliferation induced by light emitting diode and low power laser irradiation.
CONCLUSION: LED and LLL irradiation resulted in an increased fibroblast proliferation in vitro. This study therefore postulates possible stimulatory effects on wound healing in vivo at the applied dosimetric parameters.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12928819&query_hl=18&itool=pubmed_DocSum

Effectiveness of low-level laser therapy in temporomandibular disorder.
CONCLUSION: Low-level laser therapy can be considered as an alternative physical modality in the management of temporomandibular disorder.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12737331&query_hl=18&itool=pubmed_DocSum

Influence of low level laser therapy on wound healing and its biological action upon myofibroblasts.
CONCLUSIONS: Laser therapy reduced the inflammatory reaction, induced increased collagen deposition and a greater proliferation of myofibroblasts in experimental cutaneous wounds. Copyright 2003 Wiley-Liss, Inc.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12605432&query_hl=18&itool=pubmed_DocSum

Low-level laser effect on neural regeneration in Gore-Tex tubes.
CONCLUSIONS: LLL irradiation may be a useful noninvasive adjunct to promote neuronal wound healing in surgically created defects repaired with expanded polytetrafluoroethylene entubulation.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=11805774&query_hl=18&itool=pubmed_DocSum

The role of laser fluence in cell viability, proliferation, and membrane integrity of wounded human skin fibroblasts following helium-neon laser irradiation.
CONCLUSIONS: Results show that 5 J/cm(2) stimulates mitochondrial activity, which leads to normalization of cell function and ultimately stimulates cell proliferation and migration of wounded fibroblasts to accelerate wound closure. Laser irradiation can modify cellular processes in a dose or fluence (J/cm(2)) dependent manner.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16444694&query_hl=18&itool=pubmed_docsum

Low-level laser therapy is an important tool to treat disorders of the maxillofacial region.
CONCLUSIONS: These results confirm that LLLT is an effective tool and is beneficial for the treatment of many disorders of the maxillofacial region.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=9796491&query_hl=1&itool=pubmed_docsum

Low-level laser therapy in the management of disorders of the maxillofacial region.
CONCLUSIONS: These preliminary results indicate that LLLT is an important tool and brings many benefits for the treatment of many disorders of the maxillofacial region.
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=9612167&query_hl=1&itool=pubmed_docsum